Ontology highlight
ABSTRACT:
SUBMITTER: Nizamoglu M
PROVIDER: S-EPMC10632429 | biostudies-literature | 2023 Nov
REPOSITORIES: biostudies-literature
Nizamoglu Mehmet M Koloko Ngassie Maunick Lefin ML Meuleman Rhode A RA Banchero Martin M Borghuis Theo T Timens Wim W Nawijn Martijn C MC Melgert Barbro N BN Heijink Irene H IH Brandsma Corry-Anke CA Burgess Janette K JK
Scientific reports 20231108 1
Abnormal deposition of extracellular matrix (ECM) in lung tissue is a characteristic of idiopathic pulmonary fibrosis (IPF). Increased collagen deposition is also accompanied by altered collagen organization. Collagen type XIV, a fibril-associated collagen, supports collagen fibril organization. Its status in IPF has not been described at the protein level yet. In this study, we utilized publicly available datasets for single-cell RNA-sequencing for characterizing collagen type XIV expression at ...[more]