The mitochondrial respiration signature of the bovine blastocyst reflects both environmental conditions of development as well as embryo quality.

ABSTRACT: The major limitation of the widespread use of IVP derived embryos is their consistent deficiencies in vitality when compared with their ex vivo derived counterparts. Although embryo metabolism is considered a useful metric of embryo quality, research connecting mitochondrial function with the developmental capacity of embryos is still lacking. Therefore, the aim of the present study was to analyse bovine embryo respiration signatures in relation to developmental capacity. This was achieved by taking advantage of two generally accepted metrics for developmental capacity: (I) environmental conditions during development (vivo vs. vitro) and (II) developmental kinetics (day 7 vs. day 8 blastocysts). Our study showed that the developmental environment affected total embryo oxygen consumption wh

SUBMITTER: Kurzella J 

PROVIDER: S-EPMC10632430 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature