Cell response and bone ingrowth to 3D printed Ti6Al4V scaffolds with Mg-incorporating sol-gel Ta₂O₅ coating.

ABSTRACT: In recent years, additive manufacturing techniques have been used to fabricate 3D titanium (Ti)-based scaffolds for production of desirable complex shapes. However, insufficient osteointegration of porous Ti-based scaffolds can elicit long-term complications (e.g., aseptic loosening) and need further revision surgery. In this study, a magnesium (Mg)-incorporating tantalum (Ta) coating was deposited on a 3D Ti6Al4V scaffold using a sol-gel method for enhancing its osteogenic properties. To evaluate the biofunction of this surface, bone mesenchymal stem cells and rabbit femoral condyle were used to assess the cell response and bone ingrowth, respectively. Ta₂O₅ coatings and Mg-incorporating Ta₂O₅ coatings were both homogeneously deposited on

SUBMITTER: Zhang B 

PROVIDER: S-EPMC10632765 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature