Age at Diagnosis of Atrial Fibrillation and Incident Dementia.

ABSTRACT:

Importance

Epidemiological evidence regarding the association between atrial fibrillation (AF) onset age and risk of incident dementia remains unexplored.

Objective

To examine whether age at AF diagnosis is associated with risk of incident dementia and its subtypes.

Design, setting, and participants

This prospective, population-based cohort study used data from UK Biobank, a public, open-access database in the UK with baseline information collected from 2006 to 2010. A total of 433 746 participants were included in the main analysis after excluding participants with a diagnosis of dementia or AF at baseline, missing data on covariates, or having dementia before AF onset during a median follow-up of 12.6 years. Data were analyzed from October to December 2022.

Expos

SUBMITTER: Zhang W 

PROVIDER: S-EPMC10632957 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature