Prevalence and risk factors of oral human papillomavirus infection among 4212 healthy adults in Hebei, China.

ABSTRACT:

Background

Human papillomavirus (HPV) infection is an essential cause of oropharyngeal squamous cell carcinoma that is increasing in incidence worldwide. However, little is known about the epidemiology of oral HPV infection among healthy adults in China.

Methods

A study in northern China was conducted in 2021 as baseline data of Diverse Life-Course Cohort (DLCC). Residents who aged above 20 were eligible to participate. Oral swab specimens and questionnaires were collected from 4226 participants. HPV DNA in oral exfoliated cells was tested by Nested Polymerase Chain Reaction approach and sequencing. Univariate and multivariate analyses were performed to assess the associations between exposure factors and oral HPV infection.

Results

Overall prevalence of oral HPV infe

SUBMITTER: Yu S 

PROVIDER: S-EPMC10634102 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature