Spatial transferability of an agent-based model to simulate Taenia solium control interventions.

ABSTRACT:

Background

Models can be used to study and predict the impact of interventions aimed at controlling the spread of infectious agents, such as Taenia solium, a zoonotic parasite whose larval stage causes epilepsy and economic loss in many rural areas of the developing nations. To enhance the credibility of model estimates, calibration against observed data is necessary. However, this process may lead to a paradoxical dependence of model parameters on location-specific data, thus limiting the model's geographic transferability.

Methods

In this study, we adopted a non-local model calibration approach to assess whether it can improve the spatial transferability of CystiAgent, our agent-based model of local-scale T. solium transmission. The calibration dataset for CystiAgent consi

SUBMITTER: Pizzitutti F 

PROVIDER: S-EPMC10634186 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature