Assessing impulse control behaviors in early Parkinson's disease: a longitudinal study.

ABSTRACT:

Objective

Impulse control behaviors (ICBs) frequently coexist with Parkinson's disease (PD). However, the predictors of ICBs in PD remain unclear, and there is limited data on the biological correlates of ICBs in PD. In this study, we examined clinical, imaging, and biological variables to identify factors associated with longitudinal changes in ICBs in early-stage PD.

Methods

The data for this study were obtained from the Parkinson's Progression Markers Initiative, an international prospective cohort study that evaluates markers of disease progression in PD. We examined clinical, imaging, and biological variables to determine their associations with ICBs over a period of up to 5 years. Cox regression models were employed to investigate the predictors of ICBs in early-stage,

SUBMITTER: Zhu X 

PROVIDER: S-EPMC10634396 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature