Clinical significance of substrate characteristics and ablation outcomes in patients with atrial fibrillation and significant functional mitral regurgitation.

ABSTRACT:

Background

Atrial fibrillation (AF) and mitral regurgitation (MR) have a complex interplay. Catheter ablation (CA) of AF may be a potential method to improve the severity of MR in AF patients.

Methods

Patients with symptomatic AF and moderate to severe MR who underwent catheter ablation from 2011 to 2021 were retrospectively included in the study. Patients' baseline characteristics and electrophysiological features were examined. These patients were classified as group 1 with improved MR and group 2 with refractory MR after CA.

Results

Fifty patients (age 60.2 ± 11.6 years, 29 males) were included in the study (32 in group 1 and 18 in group 2). Group 1 patients had a lower CHA₂DS₂-VASc score (1.7 ± 1.5 vs. 2.7 ± 1.5, P = 0.005) and had a l

SUBMITTER: Bautista JAL 

PROVIDER: S-EPMC10634397 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature