Contrasting genes conferring short- and long-term biofilm adaptation in Listeria.

ABSTRACT: Listeria monocytogenes is an opportunistic food-borne bacterium that is capable of infecting humans with high rates of hospitalization and mortality. Natural populations are genotypically and phenotypically variable, with some lineages being responsible for most human infections. The success of L. monocytogenes is linked to its capacity to persist on food and in the environment. Biofilms are an important feature that allow these bacteria to persist and infect humans, so understanding the genetic basis of biofilm formation is key to understanding transmission. We sought to investigate the biofilm-forming ability of L. monocytogenes by identifying genetic variation that underlies biofilm formation in natural populations using genome-wide association studies (GWAS). Chang

SUBMITTER: Monteith W 

PROVIDER: S-EPMC10634452 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature