Continuous renal replacement therapy (CRRT) for rhabdomyolysis.

ABSTRACT:

Background

Rhabdomyolysis is a condition that is characterised by the breakdown of skeletal muscle tissue and leakage of intracellular myocyte contents into circulating blood. Rhabdomyolysis can lead to acute kidney injury (AKI) and is a potentially life-threatening condition. Studies have indicated that continuous renal replacement therapy (CRRT) may provide benefits for people with rhabdomyolysis by removing potentially damaging myoglobin and stabilising haemodynamic and metabolic status.

Objectives

We aimed to: i) assess the efficacy of CRRT in removing myoglobin; ii) investigate the influence of CRRT on mortality and kidney-related outcomes; and iii) evaluate the safety of CRRT for the treatment of people with rhabdomyolysis.

Search methods

We searched the Cochran

SUBMITTER: Zeng X 

PROVIDER: S-EPMC10634660 | biostudies-literature | 2014 Jun

REPOSITORIES: biostudies-literature