Multilayer network associations between the exposome and childhood brain development.

ABSTRACT: Growing up in a high poverty neighborhood is associated with elevated risk for academic challenges and health problems. Here, we take a data-driven approach to exploring how measures of children's environments relate to the development of their brain structure and function in a community sample of children between the ages of 4 and 10 years. We constructed exposomes including measures of family socioeconomic status, children's exposure to adversity, and geocoded measures of neighborhood socioeconomic status, crime, and environmental toxins. We connected the exposome to two structural measures (cortical thickness and surface area, n = 170) and two functional measures (participation coefficient and clustering coefficient, n = 130). We found dense connections within expos

SUBMITTER: Simpson-Kent IL 

PROVIDER: S-EPMC10634748 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature