The prevalence of Fusobacterium nucleatum subspecies in the oral cavity stratifies by local health status.

ABSTRACT: The ubiquitous inflammophilic pathobiont Fusobacterium nucleatum is widely recognized for its strong association with a variety of human dysbiotic diseases such as periodontitis and oral/extraoral abscesses, as well as multiple types of cancer. F. nucleatum is currently subdivided into four subspecies: F. nucleatum subspecies nucleatum (Fn. nucleatum), animalis (Fn. animalis), polymorphum (Fn. polymorphum), and vincentii/fusiforme (Fn. vincentii). Although these subspecies have been historically considered as functionally interchangeable in the oral cavity, direct clinical evidence is largely lacking for this assertion. Consequently, we assembled a collection of oral clinical specimens to determine whether F. nucleatu

SUBMITTER: Krieger M 

PROVIDER: S-EPMC10634819 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature