Executive function and underlying brain network distinctions for callous-unemotional traits and conduct problems in adolescents.

ABSTRACT: The complexity of executive function (EF) impairments in youth antisocial phenotypes of callous-unemotional (CU) traits and conduct problems (CP) challenge identifying phenotypic specific EF deficits. We can redress these challenges by (1) accounting for EF measurement error and (2) testing distinct functional brain properties accounting for differences in EF. Thus, we employed a latent modeling approach for EFs (inhibition, shifting, fluency, common EF) and extracted connection density from matching contemporary EF brain models with a sample of 112 adolescents (ages 13-17, 42% female). Path analysis indicated CU traits associated with lower inhibition. Inhibition network density positively associated with inhibition, but this association was strengthened by CU and attenuated by CP. Common

SUBMITTER: Winters DE 

PROVIDER: S-EPMC10635075 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature