Consistency of the continuous flow pressure gradient despite aortic arch anomalies co-existing with coarctation.

ABSTRACT:

Aims

Severity assessment for coarctation of the aorta (CoA) is challenging due to concomitant morphological anomalies (complex CoA) and inaccurate Doppler-based indices. Promising diagnostic performance has been reported for the continuous flow pressure gradient (CFPG), but it has not been studied in complex CoA. Our objective was to characterize the effect of complex CoA and associated hemodynamics on CFPG in a clinical cohort.

Methods and results

Retrospective analysis identified discrete juxtaductal (n=25) and complex CoA (n=43; transverse arch and/or isthmus hypoplasia) patients with arm-leg systolic blood pressure gradients (BPG) within 24 hours of echocardiography for comparison to BPG by conventional Doppler indices (simplified Bernoulli equation and modified forms co

SUBMITTER: Ghorbannia A 

PROVIDER: S-EPMC10635219 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature