Unravelling the sexual developmental biology of Cystoisospora suis, a model for comparative coccidian parasite studies.

ABSTRACT:

Introduction

The apicomplexan parasite Cystoisospora suis has global significance as an enteropathogen of suckling piglets. Its intricate life cycle entails a transition from an asexual phase to sexual development, ultimately leading to the formation of transmissible oocysts.

Methods

To advance our understanding of the parasite's cellular development, we complemented previous transcriptome studies by delving into the proteome profiles at five distinct time points of in vitro cultivation through LC/MS-MS analysis.

Results

A total of 1,324 proteins were identified in the in vitro developmental stages of C. suis, and 1,082 proteins were identified as significantly differentially expressed. Data are available via ProteomeXchange with identifier

SUBMITTER: Cruz-Bustos T 

PROVIDER: S-EPMC10635411 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature