Frailty and outcomes in heart failure patients from high-, middle-, and low-income countries.

ABSTRACT:

Background and aims

There is little information on the incremental prognostic importance of frailty beyond conventional prognostic variables in heart failure (HF) populations from different country income levels.

Methods

A total of 3429 adults with HF (age 61 ± 14 years, 33% women) from 27 high-, middle- and low-income countries were prospectively studied. Baseline frailty was evaluated by the Fried index, incorporating handgrip strength, gait speed, physical activity, unintended weight loss, and self-reported exhaustion. Mean left ventricular ejection fraction was 39 ± 14% and 26% had New York Heart Association Class III/IV symptoms. Participants were followed for a median (25th to 75th percentile) of 3.1 (2.0-4.3) years. Cox proportional hazard models for death and HF hosp

SUBMITTER: Leong DP 

PROVIDER: S-EPMC10635666 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature