The grade of individual prostate cancer lesions predicted by magnetic resonance imaging and positron emission tomography.

ABSTRACT:

Background

Multiparametric magnetic resonance imaging (mpMRI) and positron emission tomography (PET) are widely used for the management of prostate cancer (PCa). However, how these modalities complement each other in PCa risk stratification is still largely unknown. We aim to provide insights into the potential of mpMRI and PET for PCa risk stratification.

Methods

We analyzed data from 55 consecutive patients with elevated prostate-specific antigen and biopsy-proven PCa enrolled in a prospective study between December 2016 and December 2019. [⁶⁸Ga]PSMA-11 PET (PSMA-PET), [¹¹C]Acetate PET (Acetate-PET) and mpMRI were co-registered with whole-mount histopathology. Lower- and higher-grade lesions were defined by International Society of Urological Patholog

SUBMITTER: Nilsson E 

PROVIDER: S-EPMC10636013 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature