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Diagnostic performance of a deep learning-based method in differentiating malignant from benign subcentimeter (≤10 mm) solid pulmonary nodules.


ABSTRACT: This study assessed the diagnostic performance of a deep learning (DL)-based model for differentiating malignant subcentimeter (≤10 mm) solid pulmonary nodules (SSPNs) from benign ones in computed tomography (CT) images compared against radiologists with 10 and 15 years of experience in thoracic imaging (medium-senior seniority). Overall, 200 SSPNs (100 benign and 100 malignant) were retrospectively collected. Malignancy was confirmed by pathology, and benignity was confirmed by follow-up or pathology. CT images were fed into the DL model to obtain the probability of malignancy (range, 0-100%) for each nodule. According to the diagnostic results, enrolled nodules were classified into benign, malignant, or indeterminate. The accuracy and diagnostic composition of the model were compared wit

SUBMITTER: Liu J 

PROVIDER: S-EPMC10636433 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature