Constricting Life Space and Likelihood of Neurodegenerative Disease in Community-Dwelling Older Men.

ABSTRACT:

Importance

Life space is a measure of the frequency, range, and independence of movement through the environment. There is increasing interest in life space as a holistic measure of function in older adults, but the association between change in life space and incident neurodegenerative disease is unknown.

Objective

To evaluate the association between change in life space and cognitive decline or incident neurodegenerative disease over 7 years among community-dwelling older men.

Design, setting, and participants

In this cohort study, logistic regression analyses were used to examine the association of baseline and change in life space with change in cognition unadjusted and adjusted for demographics, cardiovascular risk factors, depression, gait speed, and physical ac

SUBMITTER: Bock MA 

PROVIDER: S-EPMC10636634 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature