Practice Patterns for Organ Preservation in US Patients With Rectal Cancer, 2006-2020.

ABSTRACT:

Importance

In March 2023, the National Comprehensive Cancer Network endorsed watch and wait for those with complete clinical response to total neoadjuvant therapy. Neoadjuvant therapy is highly efficacious, so this recommendation may have broad implications, but the current trends in organ preservation in the US are unknown.

Objective

To describe organ preservation trends among patients with rectal cancer in the US from 2006 to 2020.

Design, setting, and participants

This retrospective, observational case series included adults (aged ≥18 years) with rectal adenocarcinoma managed with curative intent from 2006 to 2020 in the National Cancer Database.

Exposure

The year of treatment was the primary exposure. The type of therapy was chemotherapy, radiation, or surg

SUBMITTER: Loria A 

PROVIDER: S-EPMC10636650 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature