Safety of exercise training in multiple sclerosis: An updated systematic review and meta-analysis.

ABSTRACT:

Background

A review of the safety profile of exercise training in multiple sclerosis (MS) has not been conducted since 2013.

Objective

We undertook a systematic review and meta-analysis of randomised controlled trials (RCTs) of exercise training published since 2013 and quantified estimated population risks of clinical relapse, adverse events (AE) and serious adverse event (SAE).

Methods

Articles reporting safety outcomes from comparisons of exercise training with non-exercise among persons with MS were identified. The risk of bias was established from study's internal validity assessed using Physiotherapy Evidence Database (PEDro). Rates and estimated mean population relative risks (RRs; 95% confidence interval (CI)) of safety outcomes were calculated, and random-eff

SUBMITTER: Learmonth YC 

PROVIDER: S-EPMC10637110 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature