The use of non-invasive stool tests for verification of Helicobacter pylori eradication and clarithromycin resistance.

ABSTRACT:

Background

Clarithromycin resistance of Helicobacter pylori (H. pylori) represents a major challenge in eradication therapy. In this study, we assessed if non-invasive stool tests can be used to verify successful H. pylori eradication and determine clarithromycin resistance.

Materials and methods

In this prospective study, patients undergoing urea breath testing (UBT) for confirmation of H. pylori eradication were asked to collect the stool as both a dry fecal sample and fecal immunochemical test (FIT). Stool H. pylori antigen testing (SAT) was performed on these samples and assessed for its accuracy in eradication verification. Type and duration of antibiotic treatment were retrospectively collected from patient records and compared with clarithromycin resistance determined

SUBMITTER: Mommersteeg MC 

PROVIDER: S-EPMC10637120 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature