Four-fold increased mortality rate in patients with Wilson's disease: A population-based cohort study of 151 patients.

ABSTRACT:

Background and aims

Few studies have investigated mortality rates in patients with Wilson's disease and compared these to the general population. Here, we examined several clinical outcomes (including cardiovascular, psychiatric, neurologic conditions) in a population-based study of patients with Wilson's disease.

Method

We used nationwide registers to identify all patients with a first diagnosis of Wilson's disease between 2002 and 2020 in Sweden. Each patient was matched by age, sex, and municipality with up to 10 reference individuals from the general population. Validated registers were used to investigate outcomes up to 19 years after baseline in patients and reference individuals.

Results

We identified 151 patients with Wilson's disease matched with 1441 referen

SUBMITTER: Aberg F 

PROVIDER: S-EPMC10637123 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature