ISCEV standard pattern reversal VEP development: paediatric reference limits from 649 healthy subjects.

ABSTRACT:

Purpose

To establish the extent of agreement for ISCEV standard reference pattern reversal VEPs (prVEPs) acquired at three European centres, to determine any effect of sex, and to establish reference intervals from birth to adolescence.

Methods

PrVEPs were recorded from healthy reference infants and children, aged 2 weeks to 16 years, from three centres using closely matched but non-identical protocols. Amplitudes and peak times were modelled with orthogonal quadratic and sigmoidal curves, respectively, and two-sided limits, 2.5th and 97.5th centiles, estimated using nonlinear quantile Bayesian regression. Data were compared by centre and by sex using median quantile confidence intervals. The 'critical age', i.e. age at which P100 peak time ceased to shorten, was calculated.

SUBMITTER: Thompson DA 

PROVIDER: S-EPMC10638119 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature