Regeneration of starfish radial nerve cord restores animal mobility and unveils a new coelomocyte population.

ABSTRACT: The potential to regenerate a damaged body part is expressed to a different extent in animals. Echinoderms, in particular starfish, are known for their outstanding regenerating potential. Differently, humans have restricted abilities to restore organ systems being dependent on limited sources of stem cells. In particular, the potential to regenerate the central nervous system is extremely limited, explaining the lack of natural mechanisms that could overcome the development of neurodegenerative diseases and the occurrence of trauma. Therefore, understanding the molecular and cellular mechanisms of regeneration in starfish could help the development of new therapeutic approaches in humans. In this study, we tackle the problem of starfish central nervous system regeneration by examining the

SUBMITTER: Magalhaes F 

PROVIDER: S-EPMC10638123 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature