DNA methylation-dependent epigenetic regulation of Verticillium dahliae virulence in plants.

ABSTRACT: As a conserved epigenetic mark, DNA cytosine methylation, at the 5' position (5-mC), plays important roles in multiple biological processes, including plant immunity. However, the involvement of DNA methylation in the determinants of virulence of phytopathogenic fungi remains elusive. In this study, we profiled the DNA methylation patterns of the phytopathogenic fungus Verticillium dahliae, one of the major causal pathogens of Verticillium wilt disease that causes great losses in many crops, and explored its contribution in fungal pathogenicity. We reveal that DNA methylation modification is present in V. dahliae and is required for its full virulence in host plants. The major enzymes responsible for the establishment of DNA methylation in V. dahliae were identified. We provided evidence t

SUBMITTER: Chen YY 

PROVIDER: S-EPMC10638132 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature