Association between type 2 diabetes and branched chain amino acids (BCAA); a case-control study.

ABSTRACT:

Background

Several amino acids and their derivatives have been implicated in insulin resistance (IR) and Type 2 Diabetes Mellitus (T2DM). This research sought to establish a relationship between the dietary levels of branched-chain amino acids (BCAA) and the risk of T2DM.

Methods

This case-control study was carried out on 4200 participants consisting of 589 people with T2DM and 3611 non-diabetic aged 35 to 70 years residents in Sabzevar, Iran. Data on the economic-social, employment status, medical history, lifestyle, and sleep habits were collected via interview. The food frequency questionnaire (FFQ) was used to check the nutritional status. Participants' dietary BCAA consumption was estimated using Nutritionist IV software.

Results

A significant negative associatio

SUBMITTER: Torki SA 

PROVIDER: S-EPMC10638320 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature