Stoma-free survival after anastomotic leak following rectal cancer resection: worldwide cohort of 2470 patients.

ABSTRACT:

Background

The optimal treatment of anastomotic leak after rectal cancer resection is unclear. This worldwide cohort study aimed to provide an overview of four treatment strategies applied.

Methods

Patients from 216 centres and 45 countries with anastomotic leak after rectal cancer resection between 2014 and 2018 were included. Treatment was categorized as salvage surgery, faecal diversion with passive or active (vacuum) drainage, and no primary/secondary faecal diversion. The primary outcome was 1-year stoma-free survival. In addition, passive and active drainage were compared using propensity score matching (2 : 1).

Results

Of 2470 evaluable patients, 388 (16.0 per cent) underwent salvage surgery, 1524 (62.0 per cent) passive drainage, 278 (11.0 per cent) active dra

SUBMITTER: Greijdanus NG 

PROVIDER: S-EPMC10638542 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature