The Hand and Wrist: AntImicrobials and Infection (HAWAII) trial.

ABSTRACT:

Background

Hand trauma, comprising injuries to both the hand and wrist, affects over five million people per year in the NHS, resulting in 250 000 operations each year. Surgical site infection (SSI) following hand trauma surgery leads to significant morbidity. Triclosan-coated sutures may reduce SSI in major abdominal surgery but have never been tested in hand trauma. Feasibility needs to be ascertained before a definitive trial can be delivered in hand trauma.

Methods

A multicentre feasibility RCT of antimicrobial sutures versus standard sutures involving adults undergoing surgery for hand trauma to evaluate feasibility for a definitive trial. Secondary objectives were incidence of SSI in both groups, hand function measured with patient-reported outcome measures, health-rel

SUBMITTER: Wormald JCR 

PROVIDER: S-EPMC10638545 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature