Effects of COVID-19 infection in patients with autoimmune pulmonary alveolar proteinosis: a single-center study.

ABSTRACT:

Background

Autoimmune pulmonary alveolar proteinosis (aPAP) is a rare interstitial lung disease. COVID-19 is associated with worse prognosis in previous lung diseases patients. But the prognosis of aPAP patients after infection with COVID-19 is unclear. In December 2022, China experienced a large-scale outbreak of Omicron variant of the SARS-CoV-2. In this study, we aim to explore the clinical outcomes of aPAP patients infected with COVID-19.

Results

A total of 39 aPAP patients were included in this study. 30.77% patients had a decrease in oxygen saturation after COVID-19 infection. We compared the two groups of patients with or without decreased oxygen saturation after COVID-19 infection and found that patients who had previous oxygen therapy (decreased oxygen saturation vs

SUBMITTER: Duan C 

PROVIDER: S-EPMC10638736 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature