Biomarkers for the Progression of Intermediate Age-Related Macular Degeneration.

ABSTRACT: Age-related macular degeneration (AMD) is a leading cause of severe vision loss worldwide, with a global prevalence that is predicted to substantially increase. Identifying early biomarkers indicative of progression risk will improve our ability to assess which patients are at greatest risk of progressing from intermediate AMD (iAMD) to vision-threatening late-stage AMD. This is key to ensuring individualized management and timely intervention before substantial structural damage. Some structural biomarkers suggestive of AMD progression risk are well established, such as changes seen on color fundus photography and more recently optical coherence tomography (drusen volume, pigmentary abnormalities). Emerging biomarkers identified through multimodal imaging, including reticular pseudodrusen

SUBMITTER: Lad EM 

PROVIDER: S-EPMC10640447 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature