A brain model of altered self-appraisal in social anxiety disorder.

ABSTRACT: The brain's default mode network has a central role in the processing of information concerning oneself. Dysfunction in this self-referential processing represents a key component of multiple mental health conditions, particularly social anxiety disorder (SAD). This case-control study aimed to clarify alterations to network dynamics present during self-appraisal in SAD participants. A total of 38 adolescents and young adults with SAD and 72 healthy control participants underwent a self-referential processing fMRI task. The task involved two primary conditions of interest: direct self-appraisal (thinking about oneself) and reflected self-appraisal (thinking about how others might think about oneself). Dynamic causal modeling and parametric empirical Bayes were then used to explore differenc

SUBMITTER: Jamieson AJ 

PROVIDER: S-EPMC10640593 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature