Effect of Dietary Sodium on Blood Pressure: A Crossover Trial.

ABSTRACT:

Importance

Dietary sodium recommendations are debated partly due to variable blood pressure (BP) response to sodium intake. Furthermore, the BP effect of dietary sodium among individuals taking antihypertensive medications is understudied.

Objectives

To examine the distribution of within-individual BP response to dietary sodium, the difference in BP between individuals allocated to consume a high- or low-sodium diet first, and whether these varied according to baseline BP and antihypertensive medication use.

Design, setting, and participants

Prospectively allocated diet order with crossover in community-based participants enrolled between April 2021 and February 2023 in 2 US cities. A total of 213 individuals aged 50 to 75 years, including those with normotension (25%

SUBMITTER: Gupta DK 

PROVIDER: S-EPMC10640704 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature