Sex differences in trigeminal neuralgia: a focus on radiological and clinical characteristics.

ABSTRACT:

Background

It is well established that trigeminal neuralgia is more prevalent in females than in males. Neurovascular compression with morphological changes of the trigeminal root represents the most recognized etiological factor. However, other factors may play a role in the framework of a multi-hit model. The primary aim of this study was to investigate sex differences in radiological and clinical characteristics of trigeminal neuralgia to better understand the multifactorial origin of this peculiar neuropathic pain condition.

Methods

In this cross-sectional study patients with a definite diagnosis of primary trigeminal neuralgia were consecutively enrolled. Each patient underwent 3T MRI with sequences dedicated to the study of neurovascular compression. Major morphologica

SUBMITTER: De Stefano G 

PROVIDER: S-EPMC10641090 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature