Selective head cooling in the acute phase of concussive injury: a neuroimaging study.

ABSTRACT:

Introduction

Neurovascular decoupling is a common consequence after brain injuries like sports-related concussion. Failure to appropriately match cerebral blood flow (CBF) with increases in metabolic demands of the brain can lead to alterations in neurological function and symptom presentation. Therapeutic hypothermia has been used in medicine for neuroprotection and has been shown to improve outcome. This study aimed to examine the real time effect of selective head cooling on healthy controls and concussed athletes via magnetic resonance spectroscopy (MRS) and arterial spin labeling (ASL) measures.

Methods

24 participants (12 controls; 12 concussed) underwent study procedures including the Post-Concussion Symptom Severity (PCSS) Rating Form and an MRI cooling protocol (pre

SUBMITTER: Walter AE 

PROVIDER: S-EPMC10641407 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature