Integrated genomic network analysis revealed potential of a druggable target for hemorrhoid treatment.

ABSTRACT: Hemorrhoids are a prevalent medical condition that necessitates effective treatment options. The current options for treatment consist of oral medications, topical applications, or surgery, yet a scarcity of highly effective drugs still exists. Genetic markers provide promising avenues for investigating the treatment of hemorrhoids, as they may reveal intricate biological mechanisms and targeted drug therapies, ultimately enhancing more precise treatment tailored to the patient. This study aims to identify new drug candidates for treating hemorrhoids through a meticulous bioinformatics approach and integrated with genomic network analysis. After extracting 21 druggable target genes using DrugBank from 293 genes connected to hemorrhoids, 87 possible drugs were selected. Three of these drugs

SUBMITTER: Adikusuma W 

PROVIDER: S-EPMC10641558 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature