Efficacy of fosinopril and amlodipine in pediatric primary hypertension: a single-center observational study.

ABSTRACT:

Objective

Fosinopril and amlodipine are commonly prescribed as first-line pharmacotherapeutic agents for pediatric hypertension, but there is a lack of comparative studies regarding the efficacy of these two drugs. We aimed to evaluate and compare the efficacy of fosinopril and amlodipine monotherapy in pediatric primary hypertension.

Methods

This was a single-center, bidirectional observational study. A total of 175 children and adolescents with primary hypertension receiving antihypertensive monotherapy from July 2020 to February 2023 were enrolled. According to antihypertensive drugs, they were divided into the fosinopril group (n = 96) and the amlodipine group (n = 79). Subgroup analysis was performed to compare the efficacy of the two groups in terms of bl

SUBMITTER: Wang H 

PROVIDER: S-EPMC10641687 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature