IgE response to Aed al 13 and Aed al 14 recombinant allergens from Aedes albopictus saliva in humans.

ABSTRACT:

Background

Mosquito bite is normally associated with mild allergic responses, but severe localized or systemic reactions are also possible. Reliable tools for the diagnosis of mosquito allergy are still unavailable. Here, we investigated the IgE response to 3 potential salivary allergens identified in the saliva of the tiger mosquito Aedes albopictus.

Methods

Serum from 55 adult individuals (28 controls and 27 allergic people), were analysed using an in-house Enzyme Linked ImmunoSorbent Assay (ELISA) against the Salivary Gland Extract (SGE) and the recombinant proteins albD7l2 (Aed al 2), albAntigen5-3 (Aed al 13) and albLIPS-2 (Aed al 14).

Results

Fifteen of the 27 (56%) individuals having hypersensitive reactions to mosquito bites had IgE

SUBMITTER: Arnoldi I 

PROVIDER: S-EPMC10641722 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature