Ontology highlight
ABSTRACT: Introduction
Time spent on screen-based sedentary activities is significantly associated with dementia risk, however, whether the associations vary by family history (FHx) of dementia is currently unknown. We aimed to examine independent associations of two prevalent types of screen-based sedentary activities (television [TV] viewing and computer use) with dementia and assess the modifying effect of FHx.Methods
We included 415,048 individuals free of dementia from the UK Biobank. Associations of TV viewing, computer use, and FHx with dementia risk were determined using Cox regression models. We estimated both multiplicative- and additive-scale interactions between TV viewing and computer use and FHx.Results
During a median follow-up of 12.6 years, 5,549 participants
SUBMITTER: Zhuang Z
PROVIDER: S-EPMC10641801 | biostudies-literature | 2023
REPOSITORIES: biostudies-literature