Composition, function, and timing: exploring the early-life gut microbiota in piglets for probiotic interventions.

ABSTRACT:

Background

The establishment of a robust gut microbiota in piglets during their early developmental stage holds the potential for long-term advantageous effects. However, the optimal timeframe for introducing probiotics to achieve this outcome remains uncertain.

Results

In the context of this investigation, we conducted a longitudinal assessment of the fecal microbiota of 63 piglets at three distinct pre-weaning time points. Simultaneously, we gathered vaginal and fecal samples from 23 sows. Employing 16S rRNA gene and metagenomic sequencing methodologies, we conducted a comprehensive analysis of the fluctuation patterns in microbial composition, functional capacity, interaction networks, and colonization resistance within the gut microbiota of piglets. As the piglets progre

SUBMITTER: Quan J 

PROVIDER: S-EPMC10641937 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature