Association among β2-adrenergic receptor autoantibodies and proximal left anterior descending artery lesions in patients with initial ST-segment elevation myocardial infarction.

ABSTRACT:

Background

β₂ -adrenergic receptor autoantibody (β₂ -AA) are widely present in patients with many different types of cardiovascular diseases. Proximal left anterior descending (LAD) artery lesions are associated with adverse prognostic events in patients with ST-segment elevation myocardial infarction (STEMI).

Hypothesis

β₂ -AA is associated with the presence of proximal LAD lesions in patients with STEMI.

Methods

A cohort of 153 patients with STEMI who underwent primary percutaneous coronary intervention (PPCI) was enrolled in the study. Baseline characteristics were compared between the proximal LAD group (n = 62) and the nonproximal LAD group (n = 91). Admission serum of patients was collected to detect the level of β₂ -A

SUBMITTER: Dang W 

PROVIDER: S-EPMC10642316 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature