Insights into enhancing Centella asiatica organ cell biofactories via hairy root protein profiling.

ABSTRACT: Recent advancements in plant biotechnology have highlighted the potential of hairy roots as a biotechnological platform, primarily due to their rapid growth and ability to produce specialized metabolites. This study aimed to delve deeper into hairy root development in C. asiatica and explore the optimization of genetic transformation for enhanced bioactive compound production. Previously established hairy root lines of C. asiatica were categorized based on their centelloside production capacity into HIGH, MID, or LOW groups. These lines were then subjected to a meticulous label-free proteomic analysis to identify and quantify proteins. Subsequent multivariate and protein network analyses were conducted to discern proteome differences and commonalities. Additionally, the quant

SUBMITTER: Alcalde MA 

PROVIDER: S-EPMC10642384 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature