Epidemiology and treatment of children with hereditary angioedema in Germany: A retrospective database study.

ABSTRACT:

Background

Hereditary angioedema (HAE) is a potentially life-threatening inherited disease that causes recurrent, serious, and debilitating episodes of swelling. While evidence has improved in adult patients, data on the epidemiology and treatment of pediatric patients with HAE remain very limited. The aim of this study was to determine the incidence and prevalence of pediatric patients with HAE aged <12 years, as well as treatment patterns, co-medication, and specialties involved.

Methods

In this retrospective study (2016-2021), the German IQVIA^TM pharmacy claims (LRx) database was used to analyze prescriptions of HAE-specific treatments and co-medications.

Results

We found an HAE prevalence in pediatric patients aged <12 years of 2.51:100,000 and a 12-mon

SUBMITTER: Prenzel F 

PROVIDER: S-EPMC10642561 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature