Network meta-analysis of treatments for perineal extramammary paget's disease: Focusing on performance of recurrence prevention.

ABSTRACT:

Introduction

Perineal extramammary paget's disease (EMPD) is characterized with high recurrence rate. Although numerous therapeutic measures for this disease have been reported so far, it is unknown whether there is significant difference in their recurrence-preventing efficiency. This study aims to compare the recurrence outcomes of reported perineal EMPD treatments.

Methods

We searched public databases of for published studies concerning perineal EMPD treatments. After screening by inclusion and exclusion criteria, we extracted the data relevant to recurrence rate, and conducted network meta-analysis (NMA) by using Bayesian random-effects approach.

Results

Our analysis included 29 previous studies (involving both male and female patients) and 11 treatment designs wh

SUBMITTER: Yuan X 

PROVIDER: S-EPMC10642846 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature