Bioinspired extracellular vesicle-coated silica nanoparticles as selective delivery systems.

ABSTRACT: In recent years, there has been a breakthrough in the integration of artificial nanoplatforms with natural biomaterials for the development of more efficient drug delivery systems. The formulation of bioinspired nanosystems, combining the benefits of synthetic nanoparticles with the natural features of biological materials, provides an efficient strategy to improve nanoparticle circulation time, biocompatibility and specificity toward targeted tissues. Among others biological materials, extracellular vesicles (EVs), membranous structures secreted by many types of cells composed by a protein rich lipid bilayer, have shown a great potential as drug delivery systems themselves and in combination with artificial nanoparticles. The reason for such interest relays on their natural properties, su

SUBMITTER: Dumontel B 

PROVIDER: S-EPMC10643352 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature