Improved sperm DNA fragmentation levels in infertile men following very short abstinence of 3-4 hours.

ABSTRACT:

Background

Limited data exists on possible approaches to improve sperm DNA fragmentation index (DFI) when no identifiable cause is found. The effect of short abstinence on sperm parameters has been extensively studied, but rarely reported on the effect on DFI in infertile men. In this study, we aimed to determine whether a second ejaculate provided after very short abstinence demonstrates lower DFI rates in infertile men.

Methods

This prospective cohort study was conducted at Mount Sinai Hospital, Toronto, Canada, a tertiary university affiliated hospital. All men having DFI testing in addition to the standard semen analysis were identified via a prospectively collected database. Infertile men were instructed to provide two semen samples 3-4 hours apart (the first sample was

SUBMITTER: Karavani G 

PROVIDER: S-EPMC10643391 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature