Modeling the dynamics of leptospirosis in India.

ABSTRACT: Leptospirosis, a formidable zoonotic threat spawned by Leptospira, plagues tropical and subtropical realms. This study delves deep into tropical Indian states, namely, Kerala, Gujarat, Karnataka, Maharashtra, and Tamil Nadu, unraveling the dynamics of leptospirosis through a comprehensive mathematical model that embraces temperature-driven growth rates of Leptospira. Sensitivity analysis and parameter estimation techniques fortified the model's accuracy, unraveling the factors shaping leptospirosis transmission. Notably, the numerical results highlight the significant impact of rainfall, fishing, climate, mining, agriculture, and cattle farming on leptospirosis prevalence in the endemic states of India. Finally, our study urges resolute preventive action to control and combat leptospirosis

SUBMITTER: Antima 

PROVIDER: S-EPMC10643689 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature