Survival trends and conditional survival in primary non-metastatic esophageal cancer: a SEER population-based study and external validation.

ABSTRACT: The dynamic survival trend of patients with primary non-metastatic esophageal cancer (nMEC) is unknown. We conducted a conditional survival (CS) analysis and developed a novel nomogram to predict it. Patients with primary nMEC were identified from the Surveillance, Epidemiology, and End Results (SEER) database. Independent prognostic factors of cancer-specific survival (CSS) were identified. The log-rank test and Cox analysis were used to calculate probabilities of CS. We constructed nomograms to predict survival trends and CS probabilities based on the prognostic factors. Calibration curves and C-indexes were used for internal and external validation. A total of 9,008 patients were identified from the SEER database and 37 patients were recruited as an external validation cohort. The 1- an

SUBMITTER: Sun W 

PROVIDER: S-EPMC10643951 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature