Regional Vulnerability Indices in Youth With Persistent and Distressing Psychoticlike Experiences.

ABSTRACT:

Importance

Distressing and persistent psychoticlike experiences (PLEs) in youth are associated with greater odds of developing psychiatric conditions in adulthood. Despite this risk, it is unclear whether early PLEs show similar brain patterns compared with adults with psychiatric and neurologic conditions.

Objective

To examine the degree to which persistent and distressing PLEs exhibit neural metrics that show similarity to adults with chronic psychiatric and neurologic conditions.

Design, setting, and participants

This cohort study used Adolescent Brain Cognitive Development (ABCD) Study examining the persistence and distress associated with PLEs across the first 3 waves of data with baseline structural magnetic resonance imaging data. Analyzed data were collected b

SUBMITTER: Karcher NR 

PROVIDER: S-EPMC10644211 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature