Deep brain stimulation for essential tremor versus essential tremor plus: should we target the same spot in the thalamus?

ABSTRACT:

Background

Although ET is a phenomenologically heterogeneous condition, thalamic DBS appears to be equally effective across subtypes. We hypothesized stimulation sites optimized for individuals with essential tremor (ET) would differ from individuals with essential tremor plus syndrome (ET-plus). We examined group differences in optimal stimulation sites within the ventral thalamus and their overlap of with relevant white matter tracts. By capturing these differences, we sought to determine whether ET subtypes are associated with anatomically distinct neural pathways.

Methods

A retrospective chart review was conducted on ET patients undergoing VIM DBS at MUSC between 01/2012 and 02/2022. Clinical, demographic, neuroimaging, and DBS stimulation parameter data were collected.

SUBMITTER: Yu CH 

PROVIDER: S-EPMC10644388 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature